Authored by Megan Redshaw, J.D. via The Epoch Times<\/p>\n\n\n\n New research suggests the human papillomavirus vaccine (HPV) can trigger a rare autoimmune brain disorder that causes psychiatric or neurological symptoms following vaccination<\/strong>\u2014and is easily mistaken as psychosis in its early stages.<\/p>\n\n\n\n A recently published study<\/a> in Current Medicinal Chemistry identified a possible relationship between anti-N-methyl-d-aspartate (NMDA) receptor encephalitis and HPV vaccination.<\/p>\n\n\n\n Anti-NMDA receptor encephalitis is an acute autoimmune disorder where the body creates antibodies against the N-methyl-D-aspartate<\/a> receptors in the brain<\/strong>. NMDA is a receptor of the amino acid glutamate. Glutamate is the most abundant excitatory neurotransmitter released by the brain\u2019s nerve cells and plays a crucial role in learning and memory formation.<\/p>\n\n\n\n When the anti-NMDA antibodies attack the brain, they disrupt normal brain signaling, causing swelling\u2014or encephalitis<\/a>\u2014and a host of neuropsychiatric symptoms<\/a> such as hallucinations, cognitive disturbances, paranoia, aggression, epilepsy, movement disorder, impaired consciousness, and speech disorders. It\u2019s these symptoms that often cause the condition to be misdiagnosed in its early stage as psychosis.<\/p>\n\n\n\n The paper\u2019s author, Hsiuying Wang, is a professor of statistics at the National Yang Ming Chiao Tung University. She looked at microRNA (miRNA) biomarkers to explore the relationship between anti-NMDA receptor encephalitis and vaccination.<\/p>\n\n\n\n \u201cAlthough vaccines, such as the HPV vaccine, do not directly induce autoimmune diseases, they can potentially induce an autoimmune response<\/strong> or worsen pre-existing autoimmune conditions in certain individuals,\u201d Ms. Wang told The Epoch Times.<\/p>\n\n\n\n Ms. Wang performed a literature search and identified 16 microRNA (miRNA) biomarkers of HPV and studied biomarkers associated with anti-NMDA receptor encephalitis. The analysis revealed at least four miRNA biomarkers that the two conditions commonly share.<\/p>\n\n\n\n According to The Journal of Nutritional Biochemistry,<\/a> miRNAs regulate a range of developmental and physiological<\/a> processes and are useful biomarkers for cancer and other diseases.<\/p>\n\n\n\n Using a phylogenetic tree, Ms. Wang then analyzed the relationship of the miRNA biomarkers associated with HPV and anti-NMDA receptor encephalitis, as well as for other viruses related to anti-NMDA receptor encephalitis. A phylogenetic tree is a diagram that illustrates the evolutionary relationships between different organisms.<\/p>\n\n\n\n The study found a high degree of similarity between miRNA biomarkers associated with HPV and anti-NMDA receptor encephalitis or related vaccines when compared to overall miRNAs.<\/strong><\/p>\n\n\n\n \u201cWhile the direct causal connection between HPV and anti-NMDA receptor encephalitis is minimal, insights from the microRNA biomarker study underscore the importance of not overlooking the potential link between this condition and HPV vaccination,\u201d Dr. Wang said.<\/p>\n\n\n\n \u201cTherefore, in cases where individuals receiving the HPV vaccine develop psychiatric or neurological symptoms, a diagnosis of anti-NMDA receptor encephalitis should be considered after ruling out other complications,\u201d she added.<\/p>\n\n\n\n Anti-NMDA receptor encephalitis was first identified in 2007 by researchers who saw the condition in women with ovarian tumors. It has since become the second most common<\/a> immune-mediated encephalopathy and has presented after numerous viral illnesses, including Epstein-Barr and COVID-19. It is also associated with vaccines, including H1N1, yellow fever, TdaP-IPV booster, and COVID-19, primarily in young women.<\/p>\n\n\n\n Another notable characteristic<\/a> of anti-NMDA receptor encephalitis is that it may be triggered by tumors due to the cross-reactivity with NMDA receptors in tumors containing brain cells. Ovarian, neuroendocrine, mediastinal teratomas, testicular teratomas, and small-cell lung carcinoma have all been reported to be associated with anti-NMDA antibodies.<\/p>\n\n\n\n![\"\"\/](\"https:\/\/assets.zerohedge.com\/s3fs-public\/inline-images\/image_92%28486%29.jpg?itok=2qw41kZP\")
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Association With COVID-19 Vaccines<\/h2>\n\n\n\n