{"id":11751,"date":"2025-05-10T07:57:10","date_gmt":"2025-05-10T14:57:10","guid":{"rendered":"https:\/\/jasonsblog.ddns.net\/?p=11751"},"modified":"2025-05-10T07:57:28","modified_gmt":"2025-05-10T14:57:28","slug":"breaking-covid-19-mrna-shots-destroy-over-60-of-womens-non-renewable-egg-supply","status":"publish","type":"post","link":"https:\/\/jasonsblog.ddns.net\/index.php\/2025\/05\/10\/breaking-covid-19-mrna-shots-destroy-over-60-of-womens-non-renewable-egg-supply\/","title":{"rendered":"COVID-19 mRNA Shots Destroy Over 60% of Women\u2019s Non-Renewable Egg Supply"},"content":{"rendered":"\n<p>This is interesting, and you&#8217;d have to conclude the reason for really pushing the untested and highly experimental gene therapy on pregnant women, because they were trying to reproduce and hadn&#8217;t been persuaded to abort or sacrifice parenthood for their careers. Since the west had been pretty successful in harming their citizens with the gene therapy, was this the reason for unmitigated migration?<\/p>\n\n\n\n<p><a href=\"https:\/\/www.thefocalpoints.com\/p\/breaking-covid-19-mrna-shots-destroy\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.thefocalpoints.com\/p\/breaking-covid-19-mrna-shots-destroy<\/a><\/p>\n\n\n<div class=\"wp-block-ub-divider ub_divider ub-divider-orientation-horizontal\" id=\"ub_divider_ff02bbbd-0a17-4278-a8f1-6e256fba2d6e\"><div class=\"ub_divider_wrapper\" style=\"position: relative; margin-bottom: 2px; width: 100%; height: 2px; \" data-divider-alignment=\"center\"><div class=\"ub_divider_line\" style=\"border-top: 2px solid #ccc; margin-top: 2px; \"><\/div><\/div><\/div>\n\n\n<h5 class=\"wp-block-heading\">New study finds rats injected intramuscularly with human-equivalent mRNA doses suffered irreversible loss of primordial follicles \u2014 the foundation of fertility.<\/h5>\n\n\n\n<p>By Nicolas Hulscher, MPH<\/p>\n\n\n\n<p>The study titled, <strong><a href=\"https:\/\/www.mdpi.com\/2076-393X\/13\/4\/345\">Impact of mRNA and Inactivated COVID-19 Vaccines on Ovarian Reserve<\/a>, <\/strong>was recently published in the journal <em>Vaccines<\/em>:<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p><strong>Objectives<\/strong>: This study aimed to elucidate the effects of messenger RNA (mRNA) and inactivated coronavirus disease 2019 (COVID-19) vaccines on ovarian histology and reserve in rats.<\/p>\n\n\n\n<p><strong>Methods<\/strong>: Thirty female Wistar albino rats, aged 16\u201324 weeks, were randomly divided into three groups (<em>n<\/em> = 10): control, mRNA vaccine, and inactivated vaccine groups. Each vaccine group received two doses (on day 0 and day 28) at human-equivalent doses. Four weeks post-second vaccination, ovarian tissues were harvested for analysis.<\/p>\n\n\n\n<p><strong>Results:<\/strong> Immunohistochemical analysis was performed to evaluate the expression of transforming growth factor beta-1 (TGF-\u03b21), vascular endothelial growth factor (VEGF), caspase-3, and anti-M\u00fcllerian hormone (AMH) in ovarian follicles. Both vaccines induced significant increases in TGF-\u03b21, VEGF, and caspase-3 expression, with more pronounced effects in the mRNA vaccine group. Conversely, AMH expression in the granulosa cells of primary, secondary, and antral follicles showed marked reductions (<em>p<\/em> &lt; 0.001). The counts of primordial, primary, and secondary follicles decreased significantly in the inactivated vaccine group relative to controls and further in the mRNA vaccine group compared to the inactivated group (<em>p<\/em> &lt; 0.001). Additionally, the mRNA vaccine group exhibited a decrease in antral and preovulatory follicles and an increase in atretic follicles compared to the other groups (<em>p<\/em> &lt; 0.05). The serum AMH level was diminished with the mRNA vaccination in comparison with the control and inactivated groups.<\/p>\n\n\n\n<p><strong>Conclusions<\/strong>: Our findings suggest that both mRNA and inactivated COVID-19 vaccines may detrimentally impact ovarian reserve in rats, primarily through accelerated follicular loss and alterations in apoptotic pathways during folliculogenesis. Given these observations in a rat model, further investigations into the vaccines\u2019 effects on human ovarian reserve are needed.<\/p>\n<\/blockquote>\n\n\n\n<figure class=\"wp-block-image\"><a class=\"image-link image2 is-viewable-img\" href=\"https:\/\/substackcdn.com\/image\/fetch\/f_auto,q_auto:good,fl_progressive:steep\/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Ff6946a56-2bcf-4f9b-8724-9d2ce93821c6_2480x1368.png\" target=\"_blank\" rel=\"noreferrer noopener\"><img decoding=\"async\" src=\"https:\/\/substackcdn.com\/image\/fetch\/w_2400,c_limit,f_auto,q_auto:good,fl_progressive:steep\/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Ff6946a56-2bcf-4f9b-8724-9d2ce93821c6_2480x1368.png\" alt=\"\"\/><\/a><\/figure>\n\n\n\n<h4 class=\"wp-block-heading\">Here\u2019s what the study found in simple terms:<\/h4>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Severe Destruction of Ovarian Reserve<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Rats injected intramuscularly with a Pfizer-BioNTech COVID-19 mRNA vaccine \u2014 at a human-equivalent dose \u2014 <strong>experienced a &gt;60% reduction in primordial follicles<\/strong>, the foundational egg supply for future fertility (<em>p<\/em> &lt; 0.001).<\/li>\n\n\n\n<li>The inactivated vaccine (CoronaVac) also caused loss, but to a lesser extent.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Damage Targets Non-Renewable Egg Supply<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>The <strong>primordial follicle pool is finite and non-regenerating<\/strong> \u2014 females are born with all the eggs they will ever have.<\/li>\n\n\n\n<li><strong>Destruction of this pool is irreversible<\/strong>, leading to permanent fertility loss if translated to humans.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Anti-M\u00fcllerian Hormone (AMH) Levels Crashed<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>AMH, a hormone reflecting ovarian reserve, dropped significantly in the mRNA group \u2014 both in serum and in ovarian tissue (<em>p<\/em> &lt; 0.001).<\/li>\n\n\n\n<li>Lower AMH is associated with poor fertility outcomes and earlier menopause.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Elevated Cell Death and Inflammatory Signals<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Increased expression of <strong>caspase-3<\/strong> (a cell-death enzyme) and inflammatory markers like <strong>TGF-\u03b21<\/strong> and <strong>VEGF<\/strong> were found in vaccinated rats.<\/li>\n\n\n\n<li>These biomarkers are linked to <strong>ovarian atresia<\/strong>, fibrosis, and long-term tissue damage.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>More Severe Effects with mRNA Vaccines<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Compared to the inactivated vaccine, the mRNA group had:\n<ul class=\"wp-block-list\">\n<li>Fewer growing follicles (primary, secondary, antral, preovulatory)<\/li>\n\n\n\n<li>More dying follicles (atretic)<\/li>\n\n\n\n<li>Greater reductions in hormone markers of fertility<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p>If these findings indeed apply to humans, the implications for global fertility rates are profound. This kind of damage \u2014 to a woman\u2019s lifelong egg supply \u2014 is biologically irreversible.<\/p>\n\n\n\n<p>Unfortunately, a recent study by <strong><a href=\"https:\/\/www.preprints.org\/manuscript\/202504.2487\/v1\">Manniche et al<\/a><\/strong> indicates that these ovarian reserve destruction findings likely <em>DO<\/em> translate to humans. Among ~1.3 million Czech women aged 18\u201339, those vaccinated against COVID-19 had ~33% fewer successful pregnancies compared to unvaccinated women:<\/p>\n\n\n\n<figure class=\"wp-block-image\"><a class=\"image-link image2 is-viewable-img\" href=\"https:\/\/substackcdn.com\/image\/fetch\/f_auto,q_auto:good,fl_progressive:steep\/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F38165b5d-f1d9-40ef-824f-44931a71d37d_1456x838.webp\" target=\"_blank\" rel=\"noreferrer noopener\"><img decoding=\"async\" src=\"https:\/\/substackcdn.com\/image\/fetch\/w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep\/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F38165b5d-f1d9-40ef-824f-44931a71d37d_1456x838.webp\" alt=\"\"\/><\/a><\/figure>\n\n\n\n<p>Ovarian damage likely occurs because the lipid nanoparticles encapsulating the mRNA have a particular preference for the ovaries, according to an <strong><a href=\"https:\/\/www.tga.gov.au\/sites\/default\/files\/foi-2389-06.pdf\">Australian TGA report<\/a><\/strong>:<\/p>\n\n\n\n<figure class=\"wp-block-image\"><a class=\"image-link image2 is-viewable-img\" href=\"https:\/\/substackcdn.com\/image\/fetch\/f_auto,q_auto:good,fl_progressive:steep\/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F6b9a17be-3f2e-4661-9618-e7d1da26b0e0_2400x2400.jpeg\" target=\"_blank\" rel=\"noreferrer noopener\"><img decoding=\"async\" src=\"https:\/\/substackcdn.com\/image\/fetch\/w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep\/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F6b9a17be-3f2e-4661-9618-e7d1da26b0e0_2400x2400.jpeg\" alt=\"\"\/><\/a><\/figure>\n\n\n\n<p>These data indicate that our public health agencies, in compliance with the <strong><a href=\"https:\/\/www.thefocalpoints.com\/p\/former-fda-official-reveals-bio-pharmaceutical?utm_source=publication-search\">Bio-Pharmaceutical Complex<\/a><\/strong>, have compromised the capacity to create new life across the world \u2014 by destroying ovarian reserves. And they\u2019re still doing it.<\/p>\n\n\n\n<p><strong><a href=\"https:\/\/x.com\/NicHulscher\">Nicolas Hulscher, MPH<\/a><\/strong><\/p>\n\n\n\n<p>Epidemiologist and Foundation Administrator, McCullough Foundation<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This is interesting, and you&#8217;d have to conclude the reason for really pushing the untested and highly experimental gene therapy on pregnant women, because they were trying to reproduce and hadn&#8217;t been persuaded to abort or sacrifice parenthood for their careers. Since the west had been pretty successful in harming their citizens with the gene [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5,7],"tags":[],"class_list":["post-11751","post","type-post","status-publish","format-standard","hentry","category-health","category-world"],"blocksy_meta":[],"featured_image_src":null,"author_info":{"display_name":"Jason","author_link":"https:\/\/jasonsblog.ddns.net\/index.php\/author\/jturning\/"},"_links":{"self":[{"href":"https:\/\/jasonsblog.ddns.net\/index.php\/wp-json\/wp\/v2\/posts\/11751","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/jasonsblog.ddns.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/jasonsblog.ddns.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/jasonsblog.ddns.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/jasonsblog.ddns.net\/index.php\/wp-json\/wp\/v2\/comments?post=11751"}],"version-history":[{"count":2,"href":"https:\/\/jasonsblog.ddns.net\/index.php\/wp-json\/wp\/v2\/posts\/11751\/revisions"}],"predecessor-version":[{"id":11753,"href":"https:\/\/jasonsblog.ddns.net\/index.php\/wp-json\/wp\/v2\/posts\/11751\/revisions\/11753"}],"wp:attachment":[{"href":"https:\/\/jasonsblog.ddns.net\/index.php\/wp-json\/wp\/v2\/media?parent=11751"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/jasonsblog.ddns.net\/index.php\/wp-json\/wp\/v2\/categories?post=11751"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/jasonsblog.ddns.net\/index.php\/wp-json\/wp\/v2\/tags?post=11751"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}